Minicircle and Miniplasmid DNA Vectors : (Record no. 20260)

MARC details
000 -LEADER
fixed length control field 05820cam a2200733Ia 4500
001 - CONTROL NUMBER
control field ocn828933132
003 - CONTROL NUMBER IDENTIFIER
control field OCoLC
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20220701010913.0
006 - FIXED-LENGTH DATA ELEMENTS--ADDITIONAL MATERIAL CHARACTERISTICS--GENERAL INFORMATION
fixed length control field m o d
007 - PHYSICAL DESCRIPTION FIXED FIELD--GENERAL INFORMATION
fixed length control field cr cnu|||unuuu
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 130305s2013 gw ob 001 0 eng d
040 ## - CATALOGING SOURCE
Original cataloging agency N$T
Language of cataloging eng
Description conventions pn
Transcribing agency N$T
Modifying agency E7B
-- DG1
-- CUS
-- NOC
-- OCLCO
-- YDXCP
-- OCLCA
-- NLGGC
-- OCLCF
-- EBLCP
-- UKMGB
-- IDEBK
-- DEBBG
-- OCLCQ
-- COO
-- NKT
016 7# - NATIONAL BIBLIOGRAPHIC AGENCY CONTROL NUMBER
Record control number 016300416
Source Uk
019 ## -
-- 829460534
-- 961671411
-- 962584608
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9783527670420
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 3527670424
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 9783527670437
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
ISBN 3527670432
Qualifying information (electronic bk.)
020 ## - INTERNATIONAL STANDARD BOOK NUMBER
Cancelled/invalid ISBN 9783527324569
029 1# - (OCLC)
OCLC library identifier AU@
System control number 000051628906
029 1# - (OCLC)
OCLC library identifier AU@
System control number 000053032883
029 1# - (OCLC)
OCLC library identifier CHBIS
System control number 010026927
029 1# - (OCLC)
OCLC library identifier CHVBK
System control number 306231786
029 1# - (OCLC)
OCLC library identifier DEBBG
System control number BV041069692
029 1# - (OCLC)
OCLC library identifier DEBBG
System control number BV041911234
029 1# - (OCLC)
OCLC library identifier DKDLA
System control number 820120-katalog:000655911
029 1# - (OCLC)
OCLC library identifier NLGGC
System control number 372651682
029 1# - (OCLC)
OCLC library identifier NZ1
System control number 15340142
029 1# - (OCLC)
OCLC library identifier DEBBG
System control number BV043395562
035 ## - SYSTEM CONTROL NUMBER
System control number (OCoLC)828933132
Canceled/invalid control number (OCoLC)829460534
-- (OCoLC)961671411
-- (OCoLC)962584608
050 #4 - LIBRARY OF CONGRESS CALL NUMBER
Classification number QR76.6
072 #7 - SUBJECT CATEGORY CODE
Subject category code NAT
Subject category code subdivision 022000
Source bisacsh
082 04 - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 589.908734
Edition number 23
049 ## - LOCAL HOLDINGS (OCLC)
Holding library MAIN
245 00 - TITLE STATEMENT
Title Minicircle and Miniplasmid DNA Vectors :
Remainder of title The Future of Nonviral and Viral Gene Transfer /
Statement of responsibility, etc edited by Martin Schleef.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Place of publication, distribution, etc Weinheim, Germany :
Name of publisher, distributor, etc Wiley-Blackwell,
Date of publication, distribution, etc ©2013.
300 ## - PHYSICAL DESCRIPTION
Extent 1 online resource (xxi, 235 pages)
336 ## -
-- text
-- txt
-- rdacontent
337 ## -
-- computer
-- c
-- rdamedia
338 ## -
-- online resource
-- cr
-- rdacarrier
504 ## - BIBLIOGRAPHY, ETC. NOTE
Bibliography, etc Includes bibliographical references and index.
588 0# -
-- Print version record.
505 0# - FORMATTED CONTENTS NOTE
Formatted contents note Minicircle and Miniplasmid DNA Vectors: The Future of Non-Viral and Viral Gene Transfer; Contents; List of Contributors; Perface; 1 Minicircle Patents: A Short IP Overview of Optimizing Nonviral DNA Vectors; 2 Operator-Repressor Titration: Stable Plasmid Maintenance without Selectable Marker Genes; 2.1 Introduction; 2.2 Antibiotics and Metabolic Burden; 2.3 The Mechanism of ORT; 2.4 ORT Strain Development; 2.5 ORT Miniplasmids; 2.6 DNA Vaccine and Gene Therapy Vectors; 2.7 ORT-VAC: Plasmid-Based Vaccine Delivery Using Salmonella enterica; 2.8 Recombinant Protein Expression.
505 8# - FORMATTED CONTENTS NOTE
Formatted contents note 2.9 Conclusions and Future DevelopmentsReferences; 3 Selection by RNA-RNA Interaction: Maximally Minimized Antibiotic Resistance-Free Plasmids; 3.1 Gene Therapy and DNA Vaccines: Emerging Technologies; 3.1.1 Therapeutic Plasmids: General Design Principles; 3.2 Therapeutic Plasmids: Novel Design and the Problem of Selection; 3.2.1 Replication Control of ColE1-Type Plasmids as an Alternative Selection Marker; 3.2.2 The MINIback Concept: Selection by RNA-RNA Interaction; 3.2.3 Improved Production Processes by MINIback Plasmids; 3.2.4 Improving Sequence Composition; 3.2.5 Efficient Gene Transfer.
505 8# - FORMATTED CONTENTS NOTE
Formatted contents note 3.3 ConclusionsAcknowledgments; References; 4 Plasmid-Based Medicinal Products -- Focus on pFAR: A Miniplasmid Free of Antibiotic Resistance Markers; 4.1 Introduction: Rationale for the Development of Biosafe DNA Plasmid Vectors; 4.2 Specific Requirements for the Use of DNA Product as Medicines; 4.2.1 Requirements for Plasmid Quality and Purity; 4.2.2 Requirements for the Removal of Antibiotic Resistance Markers from Plasmid DNA; 4.2.2.1 Requirements for Biosafe Plasmids; 4.2.2.2 Positive Impact on the Removal of Antibiotic Resistance Markers.
505 8# - FORMATTED CONTENTS NOTE
Formatted contents note 4.2.2.3 Effect of Plasmid Size on Gene Transfer Efficiency In Vitro and In Vivo4.3 Nonviral Gene Vectors Devoid of Antibiotic Resistance Markers; 4.3.1 Generalities; 4.3.2 Selection Systems Devoid of Antibiotic Resistance Markers; 4.3.2.1 Complementation of Host Auxotrophy by a Function-Encoded Plasmid; 4.3.2.2 The Operator-Repressor Titration (ORT) System; 4.3.2.3 Protein-Based Antidote/Poison Selection Systems; 4.3.2.4 RNA-Based Selection Marker; 4.3.2.5 Suppression of a Nonsense Mutation; 4.4 The pFAR Plasmid Family; 4.4.1 Description of the Antibiotic-Free Selection System.
505 8# - FORMATTED CONTENTS NOTE
Formatted contents note 4.4.2 pFAR Vectors Promote Efficient Expression in Several Types of Mammalian Cells4.4.2.1 In Vitro Transfection Study; 4.4.2.2 In Vivo Transfection Studies; 4.4.3 Concluding Remarks on the pFAR4 Biosafe Miniplasmid; 4.5 Concluding Remarks and Perspectives; Acknowledgments; References; 5 Plasmid DNA Concatemers: Influence of Plasmid Structure on Transfection Efficiency; 5.1 Introduction; 5.2 Plasmid DNA Topology and Size; 5.3 Plasmid DNA Concatemers; 5.4 Conclusions; Acknowledgments; References; 6 Analytical Tools in Minicircle Production; 6.1 Introduction.
520 ## - SUMMARY, ETC.
Summary, etc This first title on the topic provides complete coverage, including the molecular basis, production and possible biomedical applications. Written by the most prominent academic researchers in the field as well as by researchers at one of the world's leading companies in industrial production of minicircle DNA, this practical book is aimed at everyone who is directly or indirectly involved in the development of gene therapies.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Plasmids
General subdivision Genetics.
650 #0 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Genetic engineering.
650 #2 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Plasmids.
650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Gene therapy.
650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Genetic engineering.
650 #4 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Plasmids
General subdivision Genetics.
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element NATURE
General subdivision Plants
-- Mushrooms.
Source of heading or term bisacsh
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Genetic engineering.
Source of heading or term fast
-- (OCoLC)fst00940027
650 #7 - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name as entry element Plasmids
General subdivision Genetics.
Source of heading or term fast
-- (OCoLC)fst01066381
655 #4 - INDEX TERM--GENRE/FORM
Genre/form data or focus term Electronic books.
655 #7 - INDEX TERM--GENRE/FORM
Genre/form data or focus term Electronic books.
Source of term local
700 1# - ADDED ENTRY--PERSONAL NAME
Personal name Schleef, M.
Fuller form of name (Martin)
776 08 - ADDITIONAL PHYSICAL FORM ENTRY
Display text Print version:
Title Minicircle and miniplasmid DNA vectors.
Place, publisher, and date of publication Weinheim, Germany : Wiley-Blackwell, ©2013
International Standard Book Number 9783527324569
856 40 - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://dx.doi.org/10.1002/9783527670420">http://dx.doi.org/10.1002/9783527670420</a>
Public note Wiley Online Library
994 ## -
-- 92
-- DG1

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