TY - BOOK AU - Jäger,Timo AU - Koch,Oliver AU - Flohé,L. TI - Trypanosomatid diseases: molecular routes to drug discovery T2 - Drug discovery in infectious diseases SN - 9783527670383 AV - RC119 .T79 2013eb U1 - 616.9/6 23 PY - 2013/// CY - Weinheim PB - Wiley-VCH KW - Parasitic diseases KW - Trypanosomatidae KW - MEDICAL KW - Parasitology KW - bisacsh KW - fast KW - Trypanosomiasis KW - Chemotherapy KW - Electronic books N1 - Edition statement from running title area; Includes bibliographical references and index; pt. 1. Disease burden, current treatments, medical needs, and strategic approaches -- pt. 2. Metabolic peculiarities in the trypanosomatid family guiding drug discovery -- pt. 3. Validation and selection of drug targets in kinetoplasts -- pt. 4. Examples of target-based approaches and compounds under consideration N2 - This is the first resource to provide researchers in academia and industry with an urgently needed update summarizing the current knowledge and possibilities for drug intervention against Trypanosomatides all in one volume. As such, it covers every aspect of the topic from basic research findings, via current treatments to translational approaches in drug development and includes both human and livestock diseases. The outstanding editor and contributor team reads like a Who?s Who of the field, thus guaranteeing the outstanding quality of this ready reference UR - http://dx.doi.org/10.1002/9783527670383 ER -