TY  - BOOK
AU  - Hiraku,Yūsuke
AU  - Kawanishi,Shōsuke
AU  - Ōshima,Hiroshi
TI  - Cancer and inflammation mechanisms: chemical, biological, and clinical aspects 
SN  - 9781118826553
AV  - RC268.5 
U1  - 616.99/401 23
PY  - 2014///]
CY  - Hoboken, New Jersey
PB  - Wiley
KW  - Carcinogenesis
KW  - Inflammation
KW  - Mediators
KW  - Immunological aspects
KW  - Cancer
KW  - Neoplasms
KW  - genetics
KW  - HEALTH & FITNESS
KW  - Diseases
KW  - General
KW  - bisacsh
KW  - MEDICAL
KW  - Clinical Medicine
KW  - Evidence-Based Medicine
KW  - Internal Medicine
KW  - fast
KW  - Inflammation - Immunological aspects
KW  - Electronic books
N1  - Includes index; Includes bibliographical references and index; Titlepage; Copyright; Contents; CONTRIBUTORS; PREFACE; CHAPTER 1 INFECTION, INFLAMMATION, AND CANCER: OVERVIEW; INFECTION, INFLAMMATION, AND CANCER: POSSIBLE MECHANISMS; PRODUCTION OF INFLAMMATORY MEDIATORS AND REACTIVE OXIDANTS; DNA AND PROTEIN DAMAGE BY ROSs AND RNSs; INFLAMMATION, EPIGENETIC MODIFICATION, AND microRNA; CONCLUDING REMARKS; REFERENCES; CHAPTER 2 STEM CELL THEORY AND INFLAMMATION-RELATED CANCER; CHRONIC INFLAMMATION AND CANCER; CANCER STEM CELLS; CARCINOGENIC FACTORS ARISING FROM CHRONIC INFLAMMATION; CHRONIC INFLAMMATION AND NORMAL STEM CELL FUNCTION; Inflammation and the development and regulation of cancer stem cellsconcluding remarks; references; chapter 3 epithelial-mesenchymal transition: a link between cancer and inflammation; emt: a link between cancer and inflammation; q1: how are emt-permissive, inflammatory tumor microenvironments created?; q2: which emt-promoting signals are provided by inflammatory tumor microenvironments?; q3: how do emt-promoting signals influence the migratory behavior of tumor cells?; conclusions and future prospects; references; chapter 4 role of nitrative dna damage in inflammation- related carcinogenesis; Dna damage during chronic inflammationliver fluke-induced cholangiocarcinoma; hpv-induced cervical cancer; ebv-induced nasopharyngeal carcinoma; dna damage induced by asbestos exposure; dna damage induced by carbon nanotube; soft tissue tumors and prognosis of tumor patients; conclusions and future prospects; references; chapter 5 lipid peroxidation-derived dna adducts and the role in inflammation-related carcinogenesis; lpo-derived reactive products contribute to dna damage; results and discussion; conclusions and future prospects; references; CHAPTER 6 LEVEL OF INFLAMMATION-RELATED DNA ADDUCTS IN HUMAN TISSUESLEVEL OF 4-ONE- AND 4-OHE-DERIVED DNA ADDUCTS IN HUMAN TISSUES; BIOLOGICAL PROPERTIES OF 4-ONE- AND 4-OHE-DERIVED DNA ADDUCTS; INFLAMMATION AND FORMATION OF 4-ONE; CONCLUDING REMARKS; REFERENCES; CHAPTER 7 TOLL-LIKE RECEPTORS: ROLE IN INFLAMMATION AND CANCER; TLRs AND THEIR LIGANDS; TLR SIGNALING; MYD88-DEPENDENT SIGNALING PATHWAYS; TRIF-DEPENDENT SIGNALING PATHWAYS; INNATE IMMUNE CELLS IN CANCER TISSUES; TLRs AND TUMOR MICROENVIRONMENT; TOLL-LIKE RECEPTORS IN CANCER AND TUMOR THERAPY; ANTITUMOR ACTIVITY OF TLR LIGANDS; ROLES OF TLRs IN CANCER PROGRESSIONCURRENT AND FUTURE DEVELOPMENTS; REFERENCES; CHAPTER 8 INFLAMMASOMES AND INFLAMMATION; NOD-LIKE RECEPTORS AND THE INFLAMMASOMES; THE NLRP3 INFLAMMASOME; THE IPAF INFLAMMASOME; THE NLRP1 INFLAMMASOME; THE NLRP12 INFLAMMASOME; THE NLRP7 INFLAMMASOME; THE NLRP6 INFLAMMASOME; THE AIM2 INFLAMMASOME; CYTOKINE TARGETS OF THE INFLAMMASOME; INFLAMMASOME DYSREGULATION IN DISEASE; CONCLUDING REMARKS; REFERENCES; CHAPTER 9 ACTIVATION-INDUCED CYTIDINE DEAMINASE: AN INTRINSIC GENOME MODULATOR IN INFLAMMATION-ASSOCIATED CANCER DEVELOPMENT
UR  - http://dx.doi.org/10.1002/9781118826621
ER  -