TY - BOOK AU - Dickenson,John TI - Molecular pharmacology: from DNA to drug discovery SN - 9780470684443 (cloth) U1 - 615.19 23 PY - 2013/// CY - Chichester, West Sussex, Hoboken, NJ PB - Wiley-Blackwell KW - Molecular Targeted Therapy KW - Pharmacogenetics KW - methods KW - Drug Delivery Systems KW - Drug Discovery N1 - Includes bibliographical references and index; Introduction to drug targets and molecular pharmacology -- Molecular cloning of drug targets -- G protein-coupled receptors -- Ion channels -- Transporter proteins -- Cystic fibrosis : alternative approaches to the treatment of a genetic disease -- Pharmacogenomics -- Transcription factors and gene expression -- Cellular calcium -- Genetic engineering of mice -- Signalling complexes : protein-protein interactions and lipid rafts -- Recombinant proteins and immunotherapeutics; PHR; phr ER -