000 05383cam a2200601Ia 4500
001 ocn908080324
003 OCoLC
005 20230823095531.0
006 m o d
007 cr cnu---unuuu
008 150425s2015 nju ob 001 0 eng d
040 _aEBLCP
_beng
_epn
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_dE7B
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_dRECBK
_dIDEBK
_dDG1
_dCDX
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_dDEBBG
_dEBLCP
_dOCLCQ
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_dK6U
019 _a913737030
_a961517236
_a962727173
020 _a9781118628003
_q(electronic bk.)
020 _a1118628004
_q(electronic bk.)
020 _a9781118628270
_q(electronic bk.)
020 _a1118628276
_q(electronic bk.)
020 _a1118627989
020 _a9781118627983
020 _z9781118627983
024 7 _a10.1002/9781118628003
_2doi
029 1 _aDEBBG
_bBV043397747
035 _a(OCoLC)908080324
_z(OCoLC)913737030
_z(OCoLC)961517236
_z(OCoLC)962727173
050 4 _aQP801.R47
072 7 _aMED
_x071000
_2bisacsh
072 7 _aMED
_x075000
_2bisacsh
072 7 _aSCI
_x036000
_2bisacsh
082 0 4 _a612.3/99
_223
049 _aMAIN
245 0 4 _aThe retinoids :
_bbiology, biochemistry, and disease /
_cedited by Pascal Dollé and Karen Neiderreither.
260 _aHoboken :
_bWiley,
_c©2015.
300 _a1 online resource (634 pages)
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
588 0 _aPrint version record.
505 0 _aVitamin A Metabolic and Enzymatic Pathways. Vitamin A Metabolism, Storage and Tissue Delivery Mechanisms / William S Blaner, Yang Li -- Assimilation and Conversion of Dietary Vitamin A into Bioactive Retinoids / Earl H Harrison, Carlo dela Sena's -- Intracellular Storage and Metabolic Activation of Retinoids / Joseph L Napoli, Charles R Krois -- Evolution of the Retinoic Acid Signaling Pathway / Vincent Laudet, Elisabeth Zieger, Michael Schubert -- Biochemistry and Cellular Biology of Retinoic Acid Signaling. Control of Gene Expression by Nuclear Retinoic Acid Receptors / Marilyn Carrier, Cecile Rochette-Egly -- Retinoic Acid Receptor Coregulators in Epigenetic Regulation of Target Genes / Li-Na Wei -- Retinoid Receptors / William Bourguet, Dino Moras -- How the RAR-RXR Heterodimer Recognizes the Genome / Sylvia Urban, Tao Ye, Irwin Davidson -- Retinoid Receptor-Selective Modulators / Marco-Antonio Mendoza-Parra, William Bourguet, Angel R de Lera, Hinrich Gronemeyer -- Use of Retinoid Receptor Ligands to Identify Other Nuclear Receptor Ligands / Marcia I Dawson, Zebin Xia -- The Dual Transcriptional Activity of Retinoic Acid / Noa Noy -- Retinoids, Epigenetic Changes during Stem Cell Differentiation, and Cell Lineage Choice / Lorraine J Gudas -- Retinoic Acid Signaling in Development. Retinoic Acid Signaling and Central Nervous System Development / Malcolm Maden -- The Role of Retinoic Acid in Limb Development / Gregg Duester -- Retinoic Acid Signaling and Heart Development / Stephane Zaffran, Karen Niederreither -- Retinoic Acid in the Developing Lung and Other Foregut Derivatives / Wellington V Cardoso, Felicia Chen -- Retinoic Acid and the Control of Meiotic Initiation / Josephine Bowles, Peter Koopman -- Retinoids and Physiological Functions. Retinoids and the Visual Cycle / Darwin Babino, Johannes von Lintig -- Retinoid Signaling in the Central Nervous System / Peter McCaffery, Wojciech Krezel -- Retinoid Turnover and Catabolism / A Catharine Ross, Reza Zolfaghari -- Retinoids and the Immune System / J Rodrigo Mora, Makoto Iwata -- Retinoic Acid Receptor Signaling in Post-Natal Male Germ Cell Differentiation / Manuel Mark, Norbert B Ghyselinck -- Retinoids, Disease and Therapy. Epidemiology and Prevention of Vitamin A Deficiency Disorders / Keith P West -- Retinoid Pathway Gene Mutations and the Pathophysiology of Related Visual Diseases / Yaroslav Tsybovsky, Krzysztof Palczewski -- Retinoic Acid in Acute Myeloid Leukemias / Hugues de The, Pierre Fenaux -- Advances in the Use of Retinoids in Cancer Therapy and Prevention / Michael J Spinella, Sarah J Freemantle, Ethan Dmitrovsky.
500 _aIncludes index.
520 _aThe Retinoids: Biology, Biochemistry, and Disease provides an overview and synthesis of the retinoid molecules, from basic biology to mechanisms of diseases and therapy. The book covers retinoic acid signaling from biochemical, genetic, developmental, and clinical perspectives. The text is divided into five parts, the first of which examines vitamin A metabolic and enzymatic pathways. Focus then shifts to the role of retinoic acid signaling in development, and then to retinoids and physiological function. The book concludes with chapters on retinoids, disease and therapy.
504 _aIncludes bibliographical references at the end of each chapters and index.
650 0 _aRetinoids.
650 7 _aMEDICAL
_xPharmacology.
_2bisacsh
650 7 _aMEDICAL
_xPhysiology.
_2bisacsh
650 7 _aSCIENCE
_xLife Sciences
_xHuman Anatomy & Physiology.
_2bisacsh
650 7 _aRetinoids.
_2fast
_0(OCoLC)fst01096230
655 4 _aElectronic books.
700 1 _aDollé, Pascal.
700 1 _aNiederreither, Karen.
776 0 8 _iPrint version:
_aDollé, Pascal.
_tRetinoids : Biology, Biochemistry, and Disease.
_dHoboken : Wiley, ©2015
_z9781118627983
856 4 0 _uhttp://dx.doi.org/10.1002/9781118628003
_zWiley Online Library
994 _a92
_bDG1
999 _c20704
_d20663
526 _bls