Attrition in the pharmaceutical industry : reasons, implications, and pathways forward /

Alex, Alexander A.,

Attrition in the pharmaceutical industry : reasons, implications, and pathways forward / edited by Alexander A. Alex, C. John Harris, Dennis A. Smith. - 1 online resource.

Includes index.

Attrition in drug discovery and development / Scott Boyer, Clive Brealey and Andrew M. Davis -- Compound attrition at the pre-clinical phase / Cornelis E.C.A. Hop -- Attrition in phase I / Dennis A. Smith and Thomas A. Baillie -- Compound attrition in phase II/III / Alexander Alex, C. John Harris, Wilma W. Keighley and Dennis A. Smith -- Post-marketing attrition / Dennis A. Smith -- Influence of the regulatory environment on attrition / Robert T. Clay -- Experimental screening strategies to reduce attrition risk / Marie-Claire Peakman, Matthew Troutman, Rose Gonzales and Anne Schmidt -- Medicinal chemistry strategies to prevent compound attrition / J. Richard Morphy -- Influence of phenotypic and target-based screening strategies on compound attrition and project choice / Andrew Bell, Wolfgang Fecke and Christine Williams -- In silico approaches to address compound attrition / Peter Gedeck, Christian Kramer, Richard Lewis -- Current and future strategies for improving drug discovery efficiency / Peter Mbugua Njogu and Kelly Chibale -- Impact of investment strategies, organizational structure and corporate environment on attrition, and future investment strategies to reduce attrition / Geoff Lawton.



9781118914342 (epub) 1118914341 (epub) 9781118819449 (pdf) 1118819446 (pdf) 9781118819586 1118819586 1118679679 (cloth) 9781118679678 (cloth)

2015030480


Pharmaceutical industry--Management.
Pharmaceutical industry--Capital productivity.
Industrial efficiency.
Drug development.
Drug development.
Industrial efficiency.
Pharmaceutical industry--Capital productivity.
Pharmaceutical industry--Management.
MEDICAL / Pharmacology


Electronic books.

HD9665.5

615.1068/5