Attrition in the pharmaceutical industry : reasons, implications, and pathways forward / edited by Alexander A. Alex, C. John Harris, Dennis A. Smith.
Material type: TextPublisher: Hoboken, New Jersey : John Wiley & Sons, 2015Description: 1 online resourceContent type:- text
- computer
- online resource
- 9781118914342 (epub)
- 1118914341 (epub)
- 9781118819449 (pdf)
- 1118819446 (pdf)
- 9781118819586
- 1118819586
- 1118679679 (cloth)
- 9781118679678 (cloth)
- 615.1068/5 23
- HD9665.5
Includes index.
Attrition in drug discovery and development / Scott Boyer, Clive Brealey and Andrew M. Davis -- Compound attrition at the pre-clinical phase / Cornelis E.C.A. Hop -- Attrition in phase I / Dennis A. Smith and Thomas A. Baillie -- Compound attrition in phase II/III / Alexander Alex, C. John Harris, Wilma W. Keighley and Dennis A. Smith -- Post-marketing attrition / Dennis A. Smith -- Influence of the regulatory environment on attrition / Robert T. Clay -- Experimental screening strategies to reduce attrition risk / Marie-Claire Peakman, Matthew Troutman, Rose Gonzales and Anne Schmidt -- Medicinal chemistry strategies to prevent compound attrition / J. Richard Morphy -- Influence of phenotypic and target-based screening strategies on compound attrition and project choice / Andrew Bell, Wolfgang Fecke and Christine Williams -- In silico approaches to address compound attrition / Peter Gedeck, Christian Kramer, Richard Lewis -- Current and future strategies for improving drug discovery efficiency / Peter Mbugua Njogu and Kelly Chibale -- Impact of investment strategies, organizational structure and corporate environment on attrition, and future investment strategies to reduce attrition / Geoff Lawton.
Description based on print version record and CIP data provided by publisher.
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